Samoléčba je důležitým pilířem zdravotnictví

Abstract: A meta-analysis involving 20,643 people looked at the risk of side effects after a single dose of metamizole and other non-opioid analgesics. The focus was on serious to potentially life-threatening side effects. Agranulocytosis, for example, is one of the most feared risks associated with metamizole use. Metamizole, at any dose, was found to be a safe drug with even fewer side effects t ...

Abstract: Androgenetic alopecia causes hair thinning in the vertex region, which may significantly impair quality of life. A survey of 2,579 pharmacy employees highlights the importance of self-medication for affected women. Nutritional supplements containing amino acids and vitamins demonstrate favourable study results in vitro and in vivo.

Abstract: Dexibuprofen, the active enantiomer of ibuprofen, acts faster and causes less stress on the body compared to ibuprofen. It effectively relieves acute somatic and visceral pain. Thus, it meets the guideline criteria: good evidence, high safety profile and patient acceptance with minimized side effects.

Abstract: Occasional constipation (OC) is prevalent but under-recognized and needs clearer guidance on evaluation and treatment. This review compares two recent expert perspectives on OC, proposing a unified, patient-centered definition. Integrating patient self-assessment and expert consensus will help pharmacists in recommending effective over-the-counter therapies, thus improving patient self-m ...

Abstract: The resolution of inflammation has to date been explained by the disappearance of inflammatory messenger substances, the production of which is suppressed by non-steroidal anti-inflammatory drugs (NSAIDs). The latest studies, however, show that the resolution of inflammation is an actively controlled process, involving specialised pro-resolving mediators. Their formation is promoted by t ...