Abstract: A meta-analysis involving 20,643 people looked at the risk of side effects after a single dose of metamizole and other non-opioid analgesics. The focus was on serious to potentially life-threatening side effects. Agranulocytosis, for example, is one of the most feared risks associated with metamizole use. Metamizole, at any dose, was found to be a safe drug with even fewer side effects t ...