Stimulant laxatives, such as bisacodyl, sodium picosulfate (SPS), and senna, are recommended to treat constipation, based on the recent AGA/ACG guideline [1], with different levels of recommendation and evidence. They all stimulate intestinal motility, as well as water and electrolyte secretion, and accelerate intestinal transit time [2, 3]. Herbal laxatives cannot be generalized to be gentler com ...