Results of two single-dose studies (randomised, single centre, crossover, open-label)
Analgesics containing readily soluble ibuprofen (e.g. as the lysinate) were developed with the aim of ensuring a more rapid relief of pain than ibuprofen acid through faster absorption in the gastroin ...
Results of a clinical study (randomised, placebo-controlled, double-blind)
Does combining ibuprofen with caffeine have advantages over ibuprofen alone in the treatment of acute pain? A randomised, placebo-controlled, double-blind study compared efficacy, safety and tolerabil ...
In this internet-based observational study, 96% of the women questioned reported that abdominal pain, cramping and discomfort sometimes interfered with their everyday activities; 44% even stated that ...
Abdominal pain is common and impairs quality of life. Many specialist societies across the world have formulated guidelines on the treatment of irritable bowel syndrome and all of them mention antispa ...
This randomised, single-blind, clinical study investigated the effects of magnesium supplementation compared with combined administration of magnesium and vitamin B6. Whilst there were no significant ...
Relief that is rapid and effective is wanted when treating pain. A double-blind, placebo-controlled study investigated the efficacy, safety and tolerability of ibuprofen lysinate, ibuprofen acid and p ...
The meta-analysis demonstrated that peppermint oil is an effective and safe medicinal agent for treating the symptoms of irritable bowel syndrome. In seven clinical studies, peppermint oil was clearly ...
The European Food Safety Authority has undertaken a comprehensive risk assessment and concluded that life-long regular consumption of caffeine of up to 400 mg daily from the age of 18 by healthy adult ...
No relevant effects on the sleep quality of subjects were found in two studies in which ibuprofen combined with 100 mg caffeine was taken three times daily. Of a total of 538 patients, medication-indu ...
A review by the Cochrane Collaboration compared the analgesic effects of a common analgesic with a combination of the analgesic and caffeine. The addition of caffeine significantly increased the propo ...
