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Omeprazole vs. Poliprotect®

Clinical trial demonstrating non-inferiority of Poliprotect for heartburn and epigastric pain in patients without erosive esophagitis


A randomised, controlled, multicentre, double-blind and double-masked study confirmed the efficacy of Poliprotect®, a molecular complex of natural ingredients designed for the protection of the gastro ...

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Author: Frederick HerbstEFSM: 2023;3:230055DOI: 10.52778/efsm.23.0055Date: 17.12.2023

Bioceramic materials emitting infrared radiation for musculoskeletal pain relief


Musculoskeletal (MSK) disorders are the leading cause of chronic pain, physical, functional impairment and loss of quality of life. About one in three people worldwide is suffering from MSK pain. The ...

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Author: Bill Giannakopoulos, PharmD, Mohamed Amessou, PhD, MBA and Eva Koscova, MD, PhD, MBA, CVTI SREFSM: 2023;3:230049DOI: 10.52778/efsm.23.0049Date: 17.12.2023

Promoted to the highest evidence class: meta-analysis supports the evidence for EA 575® in treating…


In self-limiting diseases such as acute respiratory infections, patients primarily expect relief of their symptoms, the aim being to reduce suffering and thus improve their quality of life. The result ...

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Author: Dr Lukas Uebbing and Dr Simon BraunEFSM: 2023;3:230041DOI: 10.52778/efsm.23.0041Date: 17.10.2023

Bacillus clausii's protective and restorative mechanisms in PPI-induced gut imbalance using SHIME …


Long-term use of proton pump inhibitors (PPI) may lead to gut flora imbalance, which may be restored using probiotics. The study demonstrated the probiotic effects of B. clausii on gut microbiota heal ...

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Author: Zefferino Righetto, Daniel Marquez and Marcos Perez III, MDEFSM: 2023;3:230034DOI: 10.52778/efsm.23.0034Date: 05.10.2023

Perceived effectiveness and increased quality of life after Macrogol 4000 use in patients with …


With a prevalence of 14 – 30% in Spain, constipation impacts quality of life (QoL) and general well-being in the affected population. A survey conducted through Spanish pharmacies among 100 ...

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Author: Georgina Logusso, Nuno Correia, Alexia Aran and Maria MilitaoEFSM: 2023;3:230030DOI: 10.52778/efsm.23.0030Date: 25.09.2023

Real-world data demonstrate added value of cineole over nasal spray monotherapy for rhinosinusitis


The efficacy of 1,8-cineole in treating acute rhinosinusitis has been repeatedly demonstrated in randomised-controlled double-blind trials [1, 2]. Now, a non-interventional trial under everyday condit ...

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Author: Dr. Simon Braun and Dr. Lukas UebbingEFSM: 2023;3:230028DOI: 10.52778/efsm.23.0028Date: 18.09.2023

Safety of fexofenadine as over-the-counter treatment for allergic rhinitis in Italy 


Switches of oral antihistamines (OAHs) from prescription drug to over-the-counter (OTC) status may raise safety concerns due to misuse or abuse, as seen with first-generation antihistamines. A real-wo ...

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Author: Marina Volonté, DVM, Mohamed Amessou, PhD, MBA and Maria Chiara Uboldi, PhDEFSM: 2023;3:230023DOI: 10.52778/efsm.23.0023Date: 10.09.2023

Fexofenadine: A review of its use in the treatment of urticaria in pediatric and adult populations


Urticaria is an inflammatory skin disorder primarily resulting from activation of cutaneous mast cells. The released inflammatory mediators and histamine are responsible for the development of wheals ...

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Author: Margarita Murrieta-Aguttes, MD and Mohamed Amessou, PhD, MBAEFSM: 2023;3:230014DOI: 10.52778/efsm.23.0014Date: 04.09.2023

Practical guidance for the diagnosis and management of functional abdominal cramping pain


Functional abdominal cramping pain (FACP) is a common but presently under-recognised condition. Practical recommendations for FACP diagnosis and management are lacking. A recent publication based on a ...

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Author: Daniel Marquez, Harald Weigmann and Robert LangeEFSM: 2023;3:230020DOI: 10.52778/efsm.23.0020Date: 25.08.2023

Combination of probiotics, plant extracts and micronutrients shows positive effects on the …


Functional disorders of the gastrointestinal tract cause symptoms that can have a significant impact on the quality of life. Maintaining an intact intestinal barrier is essential for preventing and tr ...

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Author: Dr. Stephan Barth, Giorgia Bulferi, Roberta Lanza, Heide De Togni and Floriana RasoEFSM: 2023;3:230011DOI: 10.52778/efsm.23.0011Date: 24.07.2023